Flandreau probably isn’t the first place you would expect to find a medical marijuana dispensary. Only about 2,200 people live in the town about 40 minutes north of Sioux Falls. But its status as a sovereign nation coupled with South Dakota’s legalization of medical marijuana last fall set the stage for the business to open even though the state’s program is far from up and running.
https://blog.tenthamendmentcenter.com/2021/08/first-medical-marijuana-dispensary-opens-in-south-dakota/