ASHWAGANDHA PROFILE (Winthania Somnifera, Indian Winter Cherry/Indian Ginseng)
1 KSM-66 Ashwagandha: The High-potency, Full Spectrum Ingredient for Stress Relief, Energy, Cognition and Immunity
2 1996 Studies on the immunomodulatory effects of Ashwagandha
3 2000, Scientific Basis for the Therapeutic Use of Withania somnifera (Ashwagandha): A Review (13 pages)
4 2018 Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis
5 2009 The alpha7 Nicotinic Acetylcholine receptor on fibro-blast-like Synovite and in Synovial Tissue from RA patients
6 2001, A BIOLOGICALLY ACTIVE CONSTITUENT OF WITHANIA SOMNIFERA (ASHWAGANDHA) WITH ANTISTRESS ACTIVITY
7 2004, Genetic and Pharmacological Evidence of a Role for GABAB Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior
8 2008, A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study
9 2004, Monograph, Withania somnifera
10 2015, Safety assessment of Withania somnifera extract standardized for Withaferin A: Acute and sub-acute toxicity study
11 2010, Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signalling
12 2011, AN OVERVIEW ON ASHWAGANDHA: A RASAYANA (REJUVENATOR) OF AYURVEDA
13 2011, THERAPEUTIC USES OF WITHANIA SOMNIFERA (ASHWAGANDHA) WITH A NOTE ON WITHANOLIDES AND ITS PHARMACOLOGICAL ACTIONS
14 2012, Differential Activities of the Two Closely Related Withanolides, Withaferin A and Withanone: Bioinformatics and Experimental Evidences - p53 is a tumor suppressor protein that regulates cell cycle and prevents cancer by inducing apoptosis, activating DNA repair mechanism and enhancing the activity of p21/WAF1. p21 is a p53-dependent inhibitor of cyclin-dependent protein kinases (CDK-2 and CDK-4) and controls the initiation of S phase in cell cycle
15 2012, Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists - 500 mg capsules of aqueous roots of Ashwagandha twice daily (maximal aerobic capacity or VO2 max). These central factors include maximal cardiac output, pulmonary diffusion, blood volume, and blood flow.
16 2014, Withanolide A Prevents Neurodegeneration by Modulating Hippocampal Glutathione Biosynthesis during Hypoxia
17 2015, Combinations of Ashwagandha Leaf Extracts Protect Brain-Derived Cells against Oxidative Stress and Induce Differentiation
18 2015, Withania somnifera Root Extract Has Potent Cytotoxic Effect against Human Malignant Melanoma Cells
19 2016, Comparative evaluation of the sexual functions and NF-κB and Nrf2 pathways of some aphrodisiac herbal extracts in male rats - Serum testosterone levels significantly increased in Tribulus and Ashwagandha groups in comparison to control group. Tribulus terrestris (known as Gokshur or Gokharu) extract was able to reduce the levels of NF-κB and increase the levels of Nrf2 and HO-1 to a much greater extent than Mucuna and Ashwagandha. Tribulus Terretris has been used for a long time for treatment of various kinds of diseases by anti-inflammatory, antidiabetic, hypolipidemic, cardiotonic, hepatoprotective, analgesic, antispasmodic, anticancer, and antibacterial activities [14, 15]. extracts of
Tribulus, Ashwagandha and Mucuna are potent enhancers of sexual function and behaviour by the increasing testosterone levels and regulation of NF-κB and Nrf2/HO–1 pathways in male rats.
20 2016 Withania somnifera Extract Protects Model Neurons from In Vitro Traumatic Injury
21 2016, Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction
22 2016, Phytochemicals and botanical extracts regulate NF-κB and Nrf2/ARE reporter activities in DI TNC1 astrocytes
23 2016 Withaferin A induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms
24 2013, Withania Somnifera root extract ameliorates Hyperbaric Hypoxia induced memory impairment in rats
25 2016. Phytochemicals and botanical extracts regulate NF-κB and Nrf2/ARE reporter activities in DI TNC1 astrocytes