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New experimental painkiller is like stronger morphine without the addiction: The drug, called AT-121, targets the same opioid receptors in the brain but also latches on to nociception receptors, that block the brain’s addiction-forming response, in a primate study in Science Translational Medicine. https://www.inverse.com/article/48605-experimental-painkiller-at-121-is-not-addictive

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