There is no question that LSD and other psychedelics have played a pivotal role in the creation of modern technology. From Francis Crick, one of the co-discoverers of the DNA helix, perceiving "the double-helix shape while on LSD," to Steve Jobs and Bill Gates both experimenting with the drug. Steve Jobs was very open about his LSD use, saying that it was "one of the two or three most important things he had done in his life."
Kerry Mullis, who won a Nobel prize in chemistry for his development in the polymerase chain reaction (PCR) (turning a single segment of DNA into millions of identical copies), said that the large amount of LSD he took in the 1960's and 1970's was "much more important than any courses [he] ever took."
Carl Sagan, one of the greatest cosmologists of the 20th centry, smoked marijuana often, spoke highly of it and even wrote an essay that appeared in a 1971 book titled Marijuana Reconsidered. THC, the psychoactive ingredient in marijuana, is the most commonly used psychedelic compound on the planet.
The list goes on, and in this recent interview with CNN members of the tech community in Silicon Valley talk about the avid use of psychedelics in aiding creative drive.